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Retatrutide works by mimicking and activating three naturally occurring hormones in the body that play key roles in appetite regulation, blood sugar management and metabolism: GLP-1 (glucagon-like peptide-1) - Promotes feelings of fullness after eating, slows gastric emptying (the rate at which food leaves the stomach), and stimulates insulin secretion to help regulate blood sugar levels

That separation is the pharmacological reason the combination is rational

Now, she says, her eating habits have leveled out, which she credits to the patches

Eden Health has paused its compounded GLP-1 program (both semaglutide and tirzepatide) for new patient enrollment as of mid-2026